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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRE11A
All Species:
33.94
Human Site:
T329
Identified Species:
53.33
UniProt:
P49959
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49959
NP_005581.2
708
80593
T329
N
P
D
N
P
K
V
T
Q
A
I
Q
S
F
C
Chimpanzee
Pan troglodytes
XP_001142343
708
80653
T329
N
P
D
N
P
K
V
T
Q
A
I
Q
S
F
C
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542244
708
80700
T329
N
P
D
N
P
K
V
T
Q
A
I
Q
S
F
C
Cat
Felis silvestris
Mouse
Mus musculus
Q61216
706
80204
T329
N
P
D
N
P
K
V
T
Q
A
I
Q
S
F
C
Rat
Rattus norvegicus
Q9JIM0
706
80103
T329
N
P
D
N
P
K
V
T
Q
A
I
Q
S
F
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513434
706
80323
S329
N
P
D
N
P
K
V
S
Q
A
I
Q
N
F
C
Chicken
Gallus gallus
Q9IAM7
700
80005
T329
N
P
D
N
P
K
V
T
Q
A
I
Q
A
F
C
Frog
Xenopus laevis
Q9W6K1
711
81112
T330
N
P
D
N
P
R
V
T
Q
E
I
E
T
F
C
Zebra Danio
Brachydanio rerio
NP_001001407
619
70401
E279
I
T
S
L
S
P
G
E
A
V
K
K
H
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523547
620
69267
G280
R
F
Y
V
S
Q
P
G
S
S
V
P
T
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23255
728
81540
P367
I
P
L
Q
T
V
R
P
M
V
C
D
E
L
L
Sea Urchin
Strong. purpuratus
XP_798167
515
58684
S179
L
A
T
F
G
L
G
S
I
R
D
E
R
L
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XGM2
720
80272
D326
L
K
D
E
S
D
I
D
P
N
D
Q
N
S
I
Baker's Yeast
Sacchar. cerevisiae
P32829
692
77632
I330
D
A
T
S
K
Y
L
I
E
Q
V
E
E
M
I
Red Bread Mold
Neurospora crassa
Q9C291
739
83526
T328
Q
N
N
R
H
E
I
T
K
R
L
M
V
I
V
Conservation
Percent
Protein Identity:
100
99.4
N.A.
93.7
N.A.
88.2
88.4
N.A.
85
73.5
72.8
61.2
N.A.
39.5
N.A.
32.6
42.6
Protein Similarity:
100
99.4
N.A.
97.1
N.A.
93.7
93.7
N.A.
92.3
85.5
85
75.2
N.A.
55.6
N.A.
50.6
56.9
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
86.6
93.3
73.3
0
N.A.
0
N.A.
6.6
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
93.3
6.6
N.A.
26.6
N.A.
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
38.1
35.3
33.8
Protein Similarity:
N.A.
N.A.
N.A.
57.9
53.3
52.5
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
40
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
0
0
0
0
0
7
47
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
54
% C
% Asp:
7
0
60
0
0
7
0
7
0
0
14
7
0
0
0
% D
% Glu:
0
0
0
7
0
7
0
7
7
7
0
20
14
0
0
% E
% Phe:
0
7
0
7
0
0
0
0
0
0
0
0
0
54
0
% F
% Gly:
0
0
0
0
7
0
14
7
0
0
0
0
0
0
7
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
7
% H
% Ile:
14
0
0
0
0
0
14
7
7
0
54
0
0
14
14
% I
% Lys:
0
7
0
0
7
47
0
0
7
0
7
7
0
0
0
% K
% Leu:
14
0
7
7
0
7
7
0
0
0
7
0
0
14
14
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
7
0
7
0
% M
% Asn:
54
7
7
54
0
0
0
0
0
7
0
0
14
0
0
% N
% Pro:
0
60
0
0
54
7
7
7
7
0
0
7
0
0
0
% P
% Gln:
7
0
0
7
0
7
0
0
54
7
0
54
0
0
0
% Q
% Arg:
7
0
0
7
0
7
7
0
0
14
0
0
7
0
0
% R
% Ser:
0
0
7
7
20
0
0
14
7
7
0
0
34
14
0
% S
% Thr:
0
7
14
0
7
0
0
54
0
0
0
0
14
0
0
% T
% Val:
0
0
0
7
0
7
54
0
0
14
14
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _